Protein Glycoengineering
Protein Glycoengineering
Our glycoengineering platform enables precise control over protein glycosylation, a critical quality attribute for therapeutic proteins. We provide end-to-end services from cell line development to comprehensive glycan characterization.
Technology Highlights
- Glycoengineered Cell Lines: CHO and HEK293 cell lines with customized glycosylation pathways
- Analytical Excellence: State-of-the-art LC-MS, HILIC-UPLC, and CE platforms
- Process Expertise: Optimized culture conditions for consistent glycan profiles
Applications
- Biosimilar and biobetter development
- Therapeutic antibody optimization
- Enzyme replacement therapy
- Vaccine development
Key Features
-
Glycosylation Engineering
Precise control of N-linked and O-linked glycosylation patterns for optimized protein function.
-
Characterization & Analysis
Comprehensive glycan profiling using LC-MS, HILIC, and capillary electrophoresis.
-
Customized Services
Tailored glycoprotein development from cell line engineering to process optimization.
Technical Capabilities
- N-glycan and O-glycan analysis
- Glycoprotein expression (CHO, HEK293)
- Glycoengineered cell line development
- LC-MS/MS glycan profiling
- Sialylation optimization
- Fc glycan modulation (therapeutic antibodies)